Question 1

What is the difference between specific and non-specific bronchial responsiveness?

1. Specific responsiveness relates to specific stimuli, such as cold air, allergens, physical or toxic stimuli.
2. Non-specific responsiveness relates to airway responses elicited by unknown stimuli.
3. Specific responsiveness implies bronchoconstriction when challenged with histamine or methacholine.
4. Specific bronchial responsiveness implies a bronchoconstrictive response when challenged with allergens.